When exploring the biochemical properties of various molecules, one frequently encountered term is the molecular weight of C-peptide. For those interested in the structural nuances of this polypeptide, understanding its precise mass is essential for research and analytical applications. This article provides an in-depth look at the chemical characterization of this molecule, focusing on its physical properties and structural composition.
The Chemical Identity of Human C-Peptide
Human C-peptide is a well-defined polypeptide chain. From a chemical perspective, it is characterized b Peptide Calculator (Molecular Weight) & Amino Acid y its specif C‑peptide is a single chain 31‑amino acid (AA 33‑63) connecting (C) polypeptide with a molecular weight of approximately 3021 daltons. ic Molecular Formula, which is generally recognized as C129H211N35O48. This complex arrangement of atoms defines its stability and behavior in laboratory settings.
When researchers assess the total mass of a peptide, they look at the summation of its amino acid residues and terminal groups. For human C-peptide, the molecular mass is consistently reported in sc Chemical formula: C129H211N35O48 ; MW (average): 3020.3 ; Application(s): Diabetes research ; Condition(s)/Topic(s): Diabetes ; Standard Delivery Time: 2-5 days ientific literature and chemical databases. You will frequently Role of C-peptide in human physiology see the C-peptide - Wikipedia Molecular Weight cited as approximately 3020.3 g/mol or 3020.3 Dalton. Some variations in reporting, such as 3020.29 g/mol or 3020.5, may occur due to the specific analytical methods used during measurement, such as mass spectroscopy.
Structural Parameters and Variations
To understand why the molecular weight is a critical metric, it helps to look at the structure of the molecule itself. C-peptide is a single-chain polypeptide composed of 31 amino acids. Because the average molecular weight of an amino acid is approximately 110Da, a 31-amino acid chain naturally aligns with a mass in the range of 3.02 kDa or approximately 3021 daltons.
It is important to distinguish between different forms of peptides. For example, while human C-peptide is typically noted as 3020.3, other variants or segments, such as Proinsulin C-Peptide (55-89), may have a different molecular weight of 3616.99. Historical research has sometimes referenced larger molecular weights, such as 10,800 or 12,000, in the context of proinsulin, the precursor molecule from which C-peptide originates. However, when isolating the specific C-peptide chain, the value remains centered around the 3.02 kDa mark.
Analytical Considerations
For those working with Human c-peptide in a laboratory or research environment, purity and verification are paramount. High-quality synthetic versions are often validated through HPLC (H A normal C-peptide range is 0.5-2.0 nanograms per milliliter. These levels can be high when your body makes more insulin than usual. Levels are low when your igh-Performance Liquid Chromatography) and m Human c-peptide | C129H211N35O48 | CID 16157840 ass spectrometry to ensure they exhibit the correct molecular weight.
* Molecular Formula: C129H211N35O48
* Average MW: 3020.3
* Structural Composition: 31 amino acid residues
* Common Unit Notation: 3020 Dalton / 3.02 kDa
Whether you are reviewing technical specifications or analyzing C peptide data for comparative research, these established parameters provide a reliable foundation. The consistency in these measurements—often cited as 3020.26 in certified reference materials—underscores the importance of precise molecular characterization in modern biochemical studies.
Summary of Findings
The study of C peptide remains a fascinating area for those interested in molecular biology and peptide synthesis. By focusing on the verified molecular weight and the molecular formula, researchers can maintain high standards of accuracy in their experimental designs. While the total mass of a peptide might seem like a simple figure, it is the result of rigorous structural verification, ensuring that the peptide used in any application meets the necessary purity and identity requirements.